Real-World Evidence & Pharmacoepidemiology
6 questions covering the whole module, mixing recall with applied scenarios. Answer everything, then submit — you’ll see your score and every explanation at once. Pass threshold: 70%. Retake as many times as you like.
What is the relationship between RWD and RWE?
A researcher needs to confirm cases of drug-induced acute kidney injury requiring a documented serum creatinine rise. Why is a large insurance claims database alone inadequate for this study?
Why does the SCCS design fail when an adverse event causes the drug being studied to be discontinued?
Why can’t confounding control methods (propensity scores, active comparator design) ever fully eliminate confounding?
How does federated network architecture (DARWIN EU, Sentinel, CNODES) resolve the tension between needing large cross-national populations and data protection laws restricting patient data transfer?
What is the "triangulation principle," and why does it make a signal more credible?